Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Aug;54(8):1946-8.
doi: 10.1128/JCM.01082-16. Epub 2016 Jun 15.

The Future of Whole-Genome Sequencing for Public Health and the Clinic

Affiliations

The Future of Whole-Genome Sequencing for Public Health and the Clinic

Marc W Allard. J Clin Microbiol. 2016 Aug.

Abstract

An American Society for Microbiology (ASM) conference titled the Conference on Rapid Next-Generation Sequencing and Bioinformatic Pipelines for Enhanced Molecular Epidemiological Investigation of Pathogens provided a venue for discussing how technologies surrounding whole-genome sequencing (WGS) are advancing microbiology. Several applications in microbial taxonomy, microbial forensics, and genomics for public health pathogen surveillance were presented at the meeting and are reviewed. All of these studies document that WGS is revolutionizing applications in microbiology and that the impact of these technologies will be profound. ASM is providing support mechanisms to promote discussions of WGS techniques to foster applications and interpretations.

PubMed Disclaimer

Comment on

  • J Clin Microbiol. 54:1949.
  • J Clin Microbiol. 54:1956.
  • J Clin Microbiol. 54:1964.
  • J Clin Microbiol. 54:1975.

References

    1. Maiden MCJ, Harrison OB. 2016. Population and functional genomics of Neisseria revealed with gene-by-gene approaches. J Clin Microbiol 54:1949–1955. doi:10.1128/JCM.00301-16. - DOI - PMC - PubMed
    1. Garritty GM. 2016. A new genomics-driven taxonomy of Bacteria and Archaea: are we there yet? J Clin Microbiol 54:1956–1963. doi:10.1128/JCM.00200-16. - DOI - PMC - PubMed
    1. Pecora ND, Li N, Allard M, Li C, Albano E, Delaney M, Dubois A, Onderdonk AB, Bry L. 2015. Genomically informed surveillance for carbapenem-resistant Enterobacteriaceae in a health care system. mBio 6(4):e01030-15. doi:10.1128/mBio.01030-15. - DOI - PMC - PubMed
    1. Schmedes SE, Sajantila A, Budowle B. 2016. Expansion of microbial forensics. J Clin Microbiol 54:1964–1974. doi:10.1128/JCM.00046-16. - DOI - PMC - PubMed
    1. Allard MW, Strain E, Melka D, Bunning K, Musser SM, Brown EW, Timme R. 2016. Practical value of food pathogen traceability through building a whole-genome sequencing network and database. J Clin Microbiol 54:1975–1983. doi:10.1128/JCM.00081-16. - DOI - PMC - PubMed

Publication types

MeSH terms

LinkOut - more resources