Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2015 Nov 6;5(3):399.
doi: 10.2484/rcr.v5i3.399. eCollection 2010.

Multiple echogenic liver masses from multifocal nodular steatosis in a 55-year-old male with chronic hepatitis C

Case Reports

Multiple echogenic liver masses from multifocal nodular steatosis in a 55-year-old male with chronic hepatitis C

Christopher Ingraham et al. Radiol Case Rep. .

Abstract

Hepatic steatosis is often seen in patients with hepatitis on screening ultrasound as generalized increased liver echogenecity. However, its nodular form can present as multiple echogenic masses, which can mimic hepatocellular carcinoma or metastasis by ultrasound and computed tomography. Small hepatocellular carcinomas are often hyperechoic and have a trend towards lower alpha-fetoprotein levels. Magnetic resonance imaging can accurately identify microscopic fat within the lesions and demonstrate lack of associated enhancing soft tissue. If this entity is not appropriately characterized using magnetic resonance imaging, it can lead to additional imaging workup and unnecessary biopsy.

Keywords: AFP, alpha-fetoprotein; AML, angiomyolipoma; CT, computed tomography; FNH, focal nodular hyperplasia; HCC, hepatocellular carcinoma; MRI, magnetic resonance imaging; US, ultrasound.

PubMed Disclaimer

Figures

Figure 1
Figure 1
A 55-year-old man with chronic hepatitis C and multifocal nodular steatosis. US shows multiple focal hyperechoic hepatic masses.
Figure 2, A-D
Figure 2, A-D
A 55-year-old man with chronic hepatitis C and multifocal nodular steatosis. Axial MRI images at two levels show multiple small, irregular areas of signal loss on the opposed-phase compared to the in-phase sequence, consistent with multifocal areas of focal fat deposition
Figure 2E
Figure 2E
A 55-year-old man with chronic hepatitis C and multifocal nodular steatosis. Fat-suppressed T2-weighted fast-spin-echo (FSE) sequence shows a homogeneous liver parenchyma without any focal lesions.
Figure 2F, G
Figure 2F, G
A 55-year-old man with chronic hepatitis C and multifocal nodular steatosis. Contrast-enhanced axial 3-D fat-suppressed fast-gradient-echo images do not show areas of arterial enhancement or washout on the portal venous phase to suggest HCC.

References

    1. Kemper J, Jung G, Poll LW, Jonkmanns C, Luthen R, Moedder U. CT and MRI findings in multifocal hepatic steatosis mimicking malignancy. Abdom Imaging. 2002;27(6):708–710. [PubMed] - PubMed
    1. Marsh JI, Gibney RG, Li DK. Hepatic hemangioma in the presence of fatty infiltration: an atypical sonographic appearance. Gastrointest Radiol. 1989;14(3):262–264. [PubMed] - PubMed
    1. Konno K, Ishida H, Sato M, Komatsuda T, Ishida J, Naganuma H. Liver tumors in fatty liver: difficulty in ultrasonic interpretation. Abdom Imaging. 2001;26(5):487–491. [PubMed] - PubMed
    1. Li D, Hann LE. A practical approach to analyzing focal lesions in the liver. Ultrasound Quarterly. 2005;21(3):187–200. [PubMed] - PubMed
    1. Quinn SE, Gosinck BB. Characteristic sonographic signs of hepatic fatty infiltration. AJR Am J Roentgenol. 1985;145(4):753–755. [PubMed] - PubMed

Publication types

LinkOut - more resources