Junk DNA Used in Cerebral Cortical Evolution
- PMID: 27311076
- DOI: 10.1016/j.neuron.2016.06.007
Junk DNA Used in Cerebral Cortical Evolution
Abstract
In this issue of Neuron, Rani et al. (2016) address important questions about the mechanisms of cerebral cortical evolution. They describe how a primate-specific long non-coding RNA titrates the levels of a microRNA that regulates an ancient signaling pathway controlling neuronal numbers.
Keywords: Notch signaling; cerebral cortical development; competing endogenous RNA; long non-coding RNA; microRNA.
Copyright © 2016. Published by Elsevier Inc.
Comment on
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A Primate lncRNA Mediates Notch Signaling during Neuronal Development by Sequestering miRNA.Neuron. 2016 Jun 15;90(6):1174-1188. doi: 10.1016/j.neuron.2016.05.005. Epub 2016 Jun 2. Neuron. 2016. PMID: 27263970 Free PMC article.
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