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Editorial
. 2016 Jun 15;90(6):1143-1145.
doi: 10.1016/j.neuron.2016.06.006.

How a Piggyback Synapse Listens in to Tune Excitatory Terminals

Tony Cijsouw  1 , Thomas Biederer  2
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Free article
Editorial

How a Piggyback Synapse Listens in to Tune Excitatory Terminals

Tony Cijsouw et al. Neuron. .
Free article

Abstract

In this issue of Neuron, Mende et al. (2016) report how axo-axonic synapses of interneurons balance the strength of glutamatergic terminals in the spinal cord. The results highlight presynaptic roles of mGluR1 receptors and of BDNF as a retrograde signal to regulate GABA synthesis and tune transmission.

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  • Sensory-Derived Glutamate Regulates Presynaptic Inhibitory Terminals in Mouse Spinal Cord.
    Mende M, Fletcher EV, Belluardo JL, Pierce JP, Bommareddy PK, Weinrich JA, Kabir ZD, Schierberl KC, Pagiazitis JG, Mendelsohn AI, Francesconi A, Edwards RH, Milner TA, Rajadhyaksha AM, van Roessel PJ, Mentis GZ, Kaltschmidt JA. Mende M, et al. Neuron. 2016 Jun 15;90(6):1189-1202. doi: 10.1016/j.neuron.2016.05.008. Epub 2016 Jun 2. Neuron. 2016. PMID: 27263971 Free PMC article.

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