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Comment
. 2016 Jul;90(1):8-10.
doi: 10.1016/j.kint.2016.05.002.

Intensive glycemic control and the risk of end-stage renal disease: an ADVANCE in the management of diabetes?

Christina M Wyatt  1 , Daniel C Cattran  2
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Free article
Comment

Intensive glycemic control and the risk of end-stage renal disease: an ADVANCE in the management of diabetes?

Christina M Wyatt et al. Kidney Int. 2016 Jul.
Free article

Abstract

Posttrial follow-up of participants randomized to intensive versus standard glycemic control in the ADVANCE trial has demonstrated a significant benefit of intensive glycemic control on the risk of end-stage renal disease. In a more detailed analysis, intensive glycemic control appears to be of benefit only before the development of clinically evident kidney disease or in patients with documented early-stage chronic kidney disease.

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