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. 2016:134:391-429.
doi: 10.1016/bs.mcb.2016.03.041. Epub 2016 Apr 23.

Zebrafish kidney development

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Zebrafish kidney development

I A Drummond et al. Methods Cell Biol. 2016.

Abstract

The kidney of the zebrafish shares many features with other vertebrate kidneys including the human kidney. Similar cell types and shared developmental and patterning mechanisms make the zebrafish pronephros a valuable model for kidney organogenesis. Here we review recent advances in studies of zebrafish pronephric development and provide experimental protocols to analyze kidney cell types and structures, measure nephron function, live image kidney cells in vivo, and probe mechanisms of kidney regeneration after injury.

Keywords: Kidney; Nephron; Organogenesis; Pronephros; Regeneration.

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