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. 2016 May 27:10:967-73.
doi: 10.2147/PPA.S106530. eCollection 2016.

Quality of life in patients with recurrent aphthous stomatitis treated with a mucoadhesive patch containing citrus essential oil

Esma Kürklü-Gürleyen  1 , Merve Öğüt-Erişen  1 , Onur Çakır  1 , Ömer Uysal  2 , Gülsüm Ak  1
Affiliations

Quality of life in patients with recurrent aphthous stomatitis treated with a mucoadhesive patch containing citrus essential oil

Esma Kürklü-Gürleyen et al. Patient Prefer Adherence. .

Abstract

Purpose: To assess 1) patient satisfaction of a mucoadhesive biopatch with citrus essential oil and 2) the change in pain severity and the oral health-related quality of life in patients with recurrent aphthous stomatitis.

Patients and methods: Thirty-seven patients with recurrent aphthous stomatitis participated in the study. Baseline records of personal data, ulcer assessment, visual analog scale, and Oral Health Impact Profile-14 were documented. A mucoadhesive patch was applied over the ulcer. Patients were recommended more applications if pain continued. On the fifth day, a post-therapy assessment was made.

Results: The mean visual analog scale scores at baseline and posttreatment were significantly different (7.3±2.11 and 4.9±2.6, respectively; P=0.001). The mean duration of pain reduced after patch application. The mean total Oral Health Impact Profile-14 scores before and after treatment showed a statistically significant difference (P=0.001). In total, 78.4% of patients reported a considerable improvement in oral functions after treatment (P=0.008).

Conclusion: The mucoadhesive biopatch containing citrus essential oil resulted in satisfying pain alleviation and restoration of oral functions with a significant improvement in the oral health-related quality of life.

Keywords: biopatch; essential oil; local therapy; pain; quality of life; recurrent aphthous stomatitis.

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Figures

Figure 1
Figure 1
The mean Oral Health Impact Profile-14 (OHIP-14) scores at baseline and after treatment.
See this image and copyright information in PMC

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