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. 2016:2016:1785409.
doi: 10.1155/2016/1785409. Epub 2016 May 22.

Diarrhoea Caused by Diffuse Metastatic Lobular Breast Cancer

Sjoerd F Bakker  1 , Willem Moolenaar  1 , Marije M van Santen  2 , Mathijs P Hendriks  3
Affiliations

Diarrhoea Caused by Diffuse Metastatic Lobular Breast Cancer

Sjoerd F Bakker et al. Case Rep Oncol Med. 2016.

Abstract

A 70-year-old woman with a history of lobular breast cancer presented to our Outpatient Clinic with diarrhoea for the past 3 years. Clinical examination and laboratory research were normal. Colonoscopy showed diffuse mild erythema and a decreased vascular pattern. Biopsies from the ascending colon, transverse colon, and descending colon showed metastases of lobular breast carcinoma. Although gastrointestinal metastases are rare in breast cancer, our case emphasizes the need for further diagnostic efforts in patients with gastrointestinal symptoms and a history of breast carcinoma.

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Figures

Figure 1
Figure 1
Macroscopic findings at colonoscopy. Ascending colon (a) and descending colon (b) are shown.
Figure 2
Figure 2
Histopathological examinations of colon biopsies reveal metastases of lobular breast carcinoma. (a) Haematoxylin-eosin (HE) staining, magnification 20x, (b) immunohistochemical staining for keratin, magnification 20x, and (c) immunohistochemical staining for oestrogen receptor, magnification 20x.
See this image and copyright information in PMC

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