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. 2016:2016:6925234.
doi: 10.1155/2016/6925234. Epub 2016 May 30.

Ewing Sarcoma of the External Ear Canal

Adem Binnetoglu  1 , Tekin Baglam  1 , Gulnur Tokuc  2 , Kiymet Kecelioglu Binnetoglu  3 , Fatma Gerin  4 , Murat Sari  1
Affiliations

Ewing Sarcoma of the External Ear Canal

Adem Binnetoglu et al. Case Rep Otolaryngol. 2016.

Abstract

Background. Ewing sarcoma (ES) is a high-grade malignant tumor that has skeletal and extraskeletal forms and consists of small round cells. In the head and neck region, reported localization of extraskeletal ES includes the larynx, thyroid gland, submandibular gland, nasal fossa, pharynx, skin, and parotid gland, but not the external ear canal. Methods. We present the unique case of a 2-year-old boy with extraskeletal ES arising from the external ear canal, mimicking auricular hematoma. Results. Surgery was performed and a VAC/IE (vincristine, adriamycin, cyclophosphamide alternating with ifosfamide, and etoposide) regimen was used for adjuvant chemotherapy for 12 months. Conclusion. The clinician should consider extraskeletal ES when diagnosing tumors localized in the head and neck region because it may be manifested by a nonspecific clinical picture mimicking common otorhinolaryngologic disorders.

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Figures

Figure 1
Figure 1
(a) Smooth, rubbery mass in the left postauricular area, displacing the conchal cartilage anteriorly and obstructing the EEC. (b) Axial CT image showing a homogenous, hypodense, solid soft tissue mass in the postauricular area. (c) Fresh, unfixed specimen after surgical removal.
Figure 2
Figure 2
(a) Tumor cells are uniform small round cells with round nuclei containing fine chromatin, high nuclear to cytoplasmic ratio, and indistinct cytoplasmic membrane (H&E; 20x). (b) Tumor cells are uniform small round cells with round nuclei containing fine chromatin, high nuclear to cytoplasmic ratio, and indistinct cytoplasmic membrane (H&E; 40x). (c) Immunohistochemical staining for vimentin (40x). (d) Immunohistochemical staining for FLI1 (40x). (e) Immunohistochemical staining for CD99 (40x).
Figure 3
Figure 3
Whole body bone scan showing no bone lesions.
See this image and copyright information in PMC

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