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Comment
. 2017 Jul;26(7):635-636.
doi: 10.1111/exd.13128. Epub 2017 Jan 4.

Vitiligo therapy: restoring immune privilege?

Katia Boniface  1 , Julien Seneschal  1   2 , Alain Taïeb  1   2 , Aksam Merched  3
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Comment

Vitiligo therapy: restoring immune privilege?

Katia Boniface et al. Exp Dermatol. 2017 Jul.

Abstract

The therapeutic hypothesis proposed by Speeckaert and van Geel in this issue (1) is based on the dramatic effects of the new drugs targeting immune privilege checkpoints (PD1/PDL, CTLA4) in current advanced melanoma therapy as major inductors of vitiligo changes in the skin. Such striking clinical manifestations cannot be classified as mere side effects without considering possible consequences for spontaneously occurring vitiligo."

Keywords: immune privilege; melanoma; vitiligo.

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