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Published Erratum
. 2016 May:7:287-288.
doi: 10.1016/j.ebiom.2016.04.021. Epub 2016 Apr 20.

Corrigendum to: "Plasma concentration of the neurofilament light protein (NFL) is a biomarker of CNS injury in HIV infection: A cross-sectional study" [EBioMedicine 3 (216) 135-140]

Magnus Gisslén, Richard W Price, Ulf Andreasson, Niklas Norgren, Staffan Nilsson, Lars Hagberg, Dietmar Fuchs, Serena Spudich, Kaj Blennow, Henrik Zetterberg
Published Erratum

Corrigendum to: "Plasma concentration of the neurofilament light protein (NFL) is a biomarker of CNS injury in HIV infection: A cross-sectional study" [EBioMedicine 3 (216) 135-140]

Magnus Gisslén et al. EBioMedicine. 2016 May.
No abstract available

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Figures

Fig. 1
Fig. 1
Association between CSF and plasma NFL and concentrations of biomarkers in 8 subject groups. Panels A–B and D–F, plot concentrations of different markers for the 8 subject groups, HIV-negative controls (HIV-neg); primary HIV infection (PHI); untreated neuroasymptomatic subjects in different CD4 cell strata (Asympt); HIV-associated dementia (HAD); and subjects on suppressive antiretroviral treatment (ART). Boxes depict median and IQR, whiskers show 10–90 percentiles and ‘+’ designate the means. Dotted horizontal lines in panels D-E show the limit of detection for HIV RNA (40 copies/mL), and in panel F the upper limit of normal for CSF neopterin (5.8 nmol/L). Panel C plot the correlation between log CSF and log plasma NFL.
Fig. 2
Fig. 2
Association between NFL and age. Panel A displays the regression lines for age to log plasma and log CSF NFL in HIV-negative controls. Age was closely correlated with plasma NFL (r = 0.792, p < 0.0001) and CSF NFL (r = 0.673, p = 0.002) in HIV-negative controls. Panel B shows plasma NFL and panel C CSF NFL plotted against age in four HIV-infected groups: HIV-associated dementia (HAD); untreated neuroasymtpomatic subjects (NA); subjects on suppressive antiretroviral treatment (ART); primary HIV-infection (PHI), and HIV-negative controls (HIV-neg).
See this image and copyright information in PMC

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