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Comment
. 2016 Sep;13(9):531-2.
doi: 10.1038/nrclinonc.2016.101. Epub 2016 Jun 21.

Screening: A risk-based framework to decide who benefits from screening

Philip E Castle  1 , Hormuzd A Katki  2
Affiliations
Comment

Screening: A risk-based framework to decide who benefits from screening

Philip E Castle et al. Nat Rev Clin Oncol. 2016 Sep.

Abstract

We believe that current controversies surrounding screening might be better approached by shifting the question from ‘does screening work?’ to ‘for whom does screening work?’ We propose a ‘rule-out/rule-in’ principle as an intellectual basis and starting point for screening. Finally, we advocate the ‘equal management of equal risks’ principle as an unifying framework for developing simplified and consistent screening guidelines and practice.

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Conflict of interest statement

Competing interests statement

The authors declare no competing interests.

Comment on

  • Population-based screening for cancer: hope and hype.
    Shieh Y, Eklund M, Sawaya GF, Black WC, Kramer BS, Esserman LJ. Shieh Y, et al. Nat Rev Clin Oncol. 2016 Sep;13(9):550-65. doi: 10.1038/nrclinonc.2016.50. Epub 2016 Apr 13. Nat Rev Clin Oncol. 2016. PMID: 27071351 Free PMC article. Review.

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