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Review
. 2016 Jan-Feb;82(1):41-99.
doi: 10.1016/j.aogh.2016.01.008.

Effects of Environmental Exposures on Fetal and Childhood Growth Trajectories

Tongzhang Zheng  1 , Jie Zhang  2 , Kathryn Sommer  3 , Bryan A Bassig  4 , Xichi Zhang  5 , Jospeh Braun  2 , Shuangqing Xu  6 , Peter Boyle  7 , Bin Zhang  8 , Kunchong Shi  2 , Stephen Buka  2 , Siming Liu  2 , Yuanyuan Li  9 , Zengmin Qian  10 , Min Dai  11 , Megan Romano  2 , Aifen Zou  8 , Karl Kelsey  2
Affiliations
Review

Effects of Environmental Exposures on Fetal and Childhood Growth Trajectories

Tongzhang Zheng et al. Ann Glob Health. 2016 Jan-Feb.

Abstract

Delayed fetal growth and adverse birth outcomes are some of the greatest public health threats to this generation of children worldwide because these conditions are major determinants of mortality, morbidity, and disability in infancy and childhood and are also associated with diseases in adult life. A number of studies have investigated the impacts of a range of environmental conditions during pregnancy (including air pollution, endocrine disruptors, persistent organic pollutants, heavy metals) on fetal and child development. The results, while provocative, have been largely inconsistent. This review summarizes up to date epidemiologic studies linking major environmental pollutants to fetal and child development and suggested future directions for further investigation.

Keywords: adverse birth outcomes; catch-up growth; child development; environmental pollutants; fetal growths; low birth weight; prenatal exposure.

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Figures

Figure 1
Figure 1
Illustration of the study design and timeline for the prenatal cohort study in Wuhan, China.
See this image and copyright information in PMC

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