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. 1978 Feb;75(2):946-50.
doi: 10.1073/pnas.75.2.946.

Assignment of genes to regions of mouse chromosomes

E M Eicher, L L Washburn

Assignment of genes to regions of mouse chromosomes

E M Eicher et al. Proc Natl Acad Sci U S A. 1978 Feb.

Abstract

A genetic mapping procedure, called the duplication-deficiency method, is described. This method permits the genetic location of a translocation to be determined within a linkage group without the use of recombination. By utilizing the duplication-deficiency method to define the genetic breakpoints for a series of translocations involving a given chromosome and integrating this information with their cytological breakpoints, obtained by Giemsa banding, a genetic map of the chromosomes is constructed whereby groups of loci are assigned to banded regions. Duplication-deficiency mapping and Giemsa banding analysis of the T(X;7)1Ct and T(7;19)145H translocations together with information from the c25H deletion have permitted mouse chromosome 7 to be divided into six and chromosome 19 into two definable genetic regions.

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References

    1. Cytogenet Cell Genet. 1975;15(3):166-76 - PubMed
    1. Chromosoma. 1973;41(2):145-58 - PubMed
    1. Genetics. 1974 Nov;78(3):905-10 - PubMed
    1. J Hered. 1974 Sep-Oct;65(5):297-300 - PubMed
    1. Chromosoma. 1974;49(2):155-60 - PubMed

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