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. 2016 Jun 21;13(6):e1002049.
doi: 10.1371/journal.pmed.1002049. eCollection 2016 Jun.

Why Most Clinical Research Is Not Useful

John P A Ioannidis  1   2
Affiliations

Why Most Clinical Research Is Not Useful

John P A Ioannidis. PLoS Med. .

Abstract

John Ioannidis argues that problem base, context placement, information gain, pragmatism, patient centeredness, value for money, feasibility, and transparency define useful clinical research. He suggests most clinical research is not useful and reform is overdue.

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Conflict of interest statement

The author is a member of the editorial board of PLOS Medicine.

References

    1. Macleod MR, Michie S, Roberts I, Dirnagl U, Chalmers I, et al. Biomedical research: increasing value, reducing waste. Lancet. 2014;383(9912):101–4. 10.1016/S0140-6736(13)62329-6 - DOI - PubMed
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