Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Apr-May;109(4-5):152-3.

Clinical Question: Nasal saline or intranasal corticosteroids to treat allergic rhinitis in children

Review

Clinical Question: Nasal saline or intranasal corticosteroids to treat allergic rhinitis in children

Stefani Madison et al. J Okla State Med Assoc. 2016 Apr-May.

Abstract

Clinical question: In pediatric populations, is nasal saline irrigation as effective as intranasal corticosteroids at relieving allergic rhinitis symptoms?

Answer: No. Intranasal steroids are more effective than nasal saline alone to reduce symptoms of allergic rhinitis (AR) in children. Combination therapy further improves symptom reduction. LEVEL OF EVIDENCE FOR THE ANSWER: B SEARCH TERMS: Allergic Rhinitis, Nasal Saline, Nasal corticosteroids, children younger than age 18. DATE SEARCH WAS CONDUCTED: August and September 2014, October 2015.

Inclusion criteria: Meta-analyses, randomized controlled trials, systematic reviews, cohort studies, nasal spray, hypertonic saline solution, nasal lavage, rhinitis, intranasal administration, nasal saline, human, English language.

Exclusion criteria: Antihistamines, Adults, Articles older than 2008.

PubMed Disclaimer

References

    1. Chen J-R, Jin L, Li X-Y. The effectiveness of nasal saline irrigation (seawater) in treatment of allergic rhinitis in children. Int J Pediatr Otorhinolaryngol. 2014;78(7):1115–1118. - PubMed
    1. de Souza Campos Fernandes S, Ribeiro de Andrade C, da Cunha Ibiapina C. Application of Peak Nasal Inspiratory Flow reference values in the treatment of allergic rhinitis. Rhinology. 2014;52(2):133–136. - PubMed
    1. Roberts G, Xatzipsalti M, Borrego LM, Custovic A, Halken S, Hellings PW, et al. Pediatric rhinitis: position paper of the European Academy of Allergy and Clinical Immunology. Allergy. 2013;68(9):1102–1116. - PubMed
    1. Satdhabudha A, Poachanukoon O. Efficacy of buffered hypertonic saline nasal irrigation in children with symptomatic allergic rhinitis: a randomized double-blind study. Int J Pediatr Otorhinolaryngol. 2012;76(4):583–588. - PubMed
    1. Khianey R, Oppenheimer J. Is nasal saline irrigation all it is cracked up to be? Ann Allergy Asthma Immunol. 2012;109(1):20–28. - PubMed

Publication types