Translocation t(9;11)(p23;q12): a primary chromosomal change in renal oncocytoma
- PMID: 2733085
- DOI: 10.1016/s0022-5347(17)38679-2
Translocation t(9;11)(p23;q12): a primary chromosomal change in renal oncocytoma
Abstract
We report the cytogenetic, clinical, radiological and pathological features of a renal oncocytoma, diagnosed accidentally in a 50-year-old man who originally presented with symptoms related to prostatic hyperplasia. All metaphases examined showed a structural chromosomal rearrangement t(9;11)(p23;q12) as the only change. The constitutional karyotype was established as 46XY. We believe that this karyotypic anomaly may represent a primary and possibly specific change characterizing this uncommon and generally benign type of tumor.
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