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. 2016 May 17:5:634.
doi: 10.1186/s40064-016-2307-1. eCollection 2016.

Keratoglobus: a close entity to megalophthalmos

Noopur Gupta  1 , Anita Ganger  1
Affiliations

Keratoglobus: a close entity to megalophthalmos

Noopur Gupta et al. Springerplus. .

Abstract

Background: Keratoglobus closely resembles buphthalmos and anterior megalophthalmos.

Findings: A 45-year-old man presented with gradually progressive, painless, diminution of vision in both eyes since childhood. On examination, visual acuity of right (RE) and left eye (LE) was 20/60 and 2/20 respectively. Clinical pictures of the patient are shown in panel A, B, C, D. Keratometry values were 46.47/47.94 D at 42/132° in RE and 46.90/47.23 D at 174/84° in LE, signifying steep, ectatic cornea. Axial lengths, anterior chamber depth and corneal thickness in RE/LE was 23.53/27.12 mm, 5.18/4.48 mm and 413/420 μm respectively. Iridodonesis was noted in left eye. Retinal evaluation of LE revealed retinal detachment (RD) with posterior staphyloma due to high myopia, hereas RE was within normal limits. Intraocular pressure was normal in both eyes. Final diagnosis was keratoglobus with LE myopic RD. The patient improved to 20/30 in right eye with no improvement in LE with scleral contact lens.

Conclusion: Keratoglobus, Megalophthalmos and Buphthalmos are exceedingly close entities and it is very essential to make correct diagnosis, as management options differ significantly for all three diseases.

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Figures

Fig. 1
Fig. 1
a Clinical picture of the patient showing diffuse thinning of cornea with outward globular protrusion. b Indentation of lower lids is shown on downward gaze, due to the protruded cornea. c, d Clinical pictures of the patient, showing bilateral clear cornea with deep anterior chamber with and stretched-out limbus
See this image and copyright information in PMC

References

    1. Dua HS, Azuara-Blanco A, Pillai CT. Cataract extraction and intraocular lens implantation in anterior megalophthalmos. J Cataract Refract Surg. 1999;25:716–719. doi: 10.1016/S0886-3350(99)00024-3. - DOI - PubMed
    1. Lockington D, Ramaesh K. Use of a novel lamellar keratoplasty with pleat technique to address the abnormal white-to-white diameter in keratoglobus. Cornea. 2015;34:239–242. doi: 10.1097/ICO.0000000000000315. - DOI - PubMed
    1. Smolek MK, Klyce SD. Is keratoconus a true ectasia? An evaluation of corneal surface area. Arch Ophthalmol. 2000;118:1179–1186. doi: 10.1001/archopht.118.9.1179. - DOI - PubMed
    1. Tsai C-K, Lai I-C, Kuo H-K, Teng M-C, Fang P-C. Anterior megalophthalmos. Med J. 2005;28:191–195. - PubMed

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