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. 2015 May 11:2:2333794X15585994.
doi: 10.1177/2333794X15585994. eCollection 2015.

Restless Legs Syndrome in Pediatric Patients With Nephrotic Syndrome

Victoria Cheung  1 , Sara Wertenteil  1 , Susan Sasson  1 , Suzanne Vento  1 , Sanjeev Kothare  1 , Howard Trachtman  1
Affiliations

Restless Legs Syndrome in Pediatric Patients With Nephrotic Syndrome

Victoria Cheung et al. Glob Pediatr Health. .

Abstract

Background. Restless legs syndrome (RLS) is a sleep disorder characterized by an urge to move or the presence of unpleasant sensations in the extremities. The prevalence of RLS is higher in children and adults with chronic kidney disease and in adults with glomerular disease. Objective. To determine the prevalence of RLS in children with nephrotic syndrome. Methods. We studied 50 children with nephrotic syndrome and 22 controls. The following surveys were administered: Pediatric Emory RLS questionnaire, Pediatric Daytime Sleepiness Scale, and Pediatric Sleep Questionnaire. Results. Children with nephrotic syndrome were 9.0 ± 4.4 years old, 27 were male, and 27 were in remission. The prevalence of RLS was similar in the nephrotic syndrome cases and controls, whether or not indeterminate cases were considered positive: 14.0% versus 13.6% including indeterminate cases, and 8.0% versus 9.1% excluding indeterminate cases. Conclusion. RLS is not more common in children with glomerular disease compared to healthy controls.

Keywords: nephrotic syndrome; pediatric; restless leg syndrome.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Characteristics of restless legs syndrome (RLS) (+) and RLS (−) nephrotic syndrome patients.
See this image and copyright information in PMC

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