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Case Reports
. 2016 Jun 16;21(24).
doi: 10.2807/1560-7917.ES.2016.21.24.30261.

Confirmed case of Zika virus congenital infection, Spain, March 2016

Sonia Perez  1 , Ruben Tato, Jorge Julio Cabrera, Alberto Lopez, Olga Robles, Eugenio Paz, Amparo Coira, Maria Paz Sanchez-Seco, Ana Vazquez, Raquel Carballo, Carlos Quintas, Anxela Pousa
Affiliations
Free article
Case Reports

Confirmed case of Zika virus congenital infection, Spain, March 2016

Sonia Perez et al. Euro Surveill. .
Free article

Abstract

We describe Zika virus (ZIKV) vertical transmission in an imported case in Spain, in a 17-week pregnant woman. ZIKV IgG, IgM and RNA were detected in serum in week 17. At 19 weeks, ultrasound scan revealed fetal malformations and ZIKV was detected in the amniotic fluid. Pregnancy was terminated at week 21; autopsy of the fetus revealed bilateral hydrocephalus, brain microcalcifications and arthrogryposis multiplex congenita. ZIKV was detected in the umbilical cord and brain tissue.

Keywords: Flaviviridae; Zika virus; imported viral diseases; pregnancy; sexually transmitted infections; surveillance; vector-borne infections.

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