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Comment
. 2016 Aug;4(8):643.
doi: 10.1158/2326-6066.CIR-16-0132. Epub 2016 Jun 23.

Remote Controlled CARs: Towards a Safer Therapy for Leukemia

Carl H June  1
Affiliations
Comment

Remote Controlled CARs: Towards a Safer Therapy for Leukemia

Carl H June. Cancer Immunol Res. 2016 Aug.

Abstract

Genetic engineering of patient T cells with chimeric antigen receptors (CAR T cells) provides a powerful tool for inducing remissions in patients with various cancers derived from B cells. Challenges stemming from the inability to control the CAR T cells once given pose significant safety concerns. An article in Cancer Immunology Research presents an approach to circumvent this issue. Cancer Immunol Res; 4(8); 643. ©2016 AACRSee article by Sakemura et al., p. 658.

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