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. 2016 Sep;86(1):118-20.
doi: 10.1016/j.diagmicrobio.2016.05.020. Epub 2016 Jun 2.

Potential clinical impact of the film array meningitis encephalitis panel in children with suspected central nervous system infections

Kevin Messacar  1 , Garrett Breazeale  2 , Christine C Robinson  2 , Samuel R Dominguez  3
Affiliations

Potential clinical impact of the film array meningitis encephalitis panel in children with suspected central nervous system infections

Kevin Messacar et al. Diagn Microbiol Infect Dis. 2016 Sep.

Abstract

The FilmArray Meningitis Encephalitis Panel, a multiplex PCR for testing of cerebrospinal fluid, was compared to conventional diagnostic methods in children with suspected central nervous system infections. The panel had comparable diagnostic yield (96% agreement) and improved time-to-diagnosis by 10.3 hours with potential for more judicious antimicrobial use, particularly acyclovir.

Keywords: Acyclovir; Central nervous system infection; Cerebrospinal fluid; Encephalitis; Meningitis; Rapid diagnostics.

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