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. 2016 Jul;12(1):169-172.
doi: 10.3892/etm.2016.3312. Epub 2016 May 9.

Clinical effects of perazine ferulate tablets combined with eucalyptol limonene pinene enteric soft capsules for treatment of children with IgA nephropathy

Zhizhen Liu  1 , Jingmei Pan  1 , Chunlei Sun  1 , Juan Zhou  1 , N A Li  1
Affiliations

Clinical effects of perazine ferulate tablets combined with eucalyptol limonene pinene enteric soft capsules for treatment of children with IgA nephropathy

Zhizhen Liu et al. Exp Ther Med. 2016 Jul.

Abstract

The clinical effects of piperazine ferulate tablets combined with eucalyptol limonene pinene enteric soft capsules for treatment of children with IgA nephropathy were investigated. Sixty children with IgA nephropathy were included in the study and were randomly divided into the control (n=30) and observation (n=30) groups. The patients in the control group were treated with conservative or hormone therapy while patients in the observation group were treated with piperazine ferulate tablets combined with eucalyptol-limonene-pinene enteric soft capsules. Clinical effects were observed and compared. The total effective rate of the observation group was significantly higher than that of the control group, while the incidence of complications was significantly lower than that of the control group (p<0.05). Serum IgA and fibronectin levels of the observation group were significantly lower than those of the control group, while the level of C3 was significantly higher than that of the control group (p<0.05). In conclusion, piperazine ferulate tablets combined with eucalyptus enteric soft capsule constituted a safe and effective for the treatment of children with IgA nephropathy. The treatment was superior to conservative or hormone therapy, and thus worthy of clinical promotion.

Keywords: IgA nephropathy; eucalyptol-limonene-pinene enteric soft capsule; piperazine ferulate tablets.

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References

    1. Hastings MC, Moldoveanu Z, Suzuki H, Berthoux F, Julian BA, Sanders JT, Renfrow MB, Novak J, Wyatt RJ. Biomarkers in IgA nephropathy: relationship to pathogenetic hits. Expert Opin Med Diagn. 2013;7:615–627. doi: 10.1517/17530059.2013.856878. - DOI - PMC - PubMed
    1. Aizawa M, Suzuki Y, Suzuki H, Pang H, Kihara M, Nakata J, Yamaji K, Horikoshi S, Tomino Y. Uncoupling of glomerular IgA deposition and disease progression in alymphoplasia mice with IgA nephropathy. PLoS One. 2014;9:e95365. doi: 10.1371/journal.pone.0095365. - DOI - PMC - PubMed
    1. Suzuki Y, Suzuki H, Nakata J, Sato D, Kajiyama T, Watanabe T, Tomino Y. Pathological role of tonsillar B cells in IgA nephropathy. Clin Dev Immunol. 2011;2011:639074. doi: 10.1155/2011/639074. - DOI - PMC - PubMed
    1. Kiryluk K, Novak J. The genetics and immunobiology of IgA nephropathy. J Clin Invest. 2014;124:2325–2332. doi: 10.1172/JCI74475. - DOI - PMC - PubMed
    1. Liu SJ, Gu Y, Li SJ, et al. Nephroprotective effects of piperazine ferulate on rat remnant kidney. Chin J Integr Trad West Nephrol. 2002;3:256–259.

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