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Review
. 2016 Jun 27;14(1):38.
doi: 10.1186/s12969-016-0101-9.

PFAPA syndrome: a review on treatment and outcome

Federica Vanoni  1 , Katerina Theodoropoulou  2 , Michaël Hofer  3
Affiliations
Review

PFAPA syndrome: a review on treatment and outcome

Federica Vanoni et al. Pediatr Rheumatol Online J. .

Abstract

The syndrome of periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA syndrome) is the most common cause of periodic fever in childhood. The current pharmacological treatment includes corticosteroids, which usually are efficacious in the management of fever episodes, colchicine, for the prophylaxis of febrile episodes, and other medication for which efficacy has not been proven so far. Tonsillectomy is an option for selected patients. Usually PFAPA syndrome resolves during adolescence, but there is increasing evidence that this condition may persist into adulthood.

Keywords: Colchicine; Glucocorticoids; PFAPA outcome; PFAPA treatment; Tonsillectomy.

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References

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