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Review
. 2016 Jun;63(2):114-23.
doi: 10.1002/jmrs.149. Epub 2016 Jan 21.

The evolving roles and controversies of radiotherapy in the treatment of glioblastoma

Eric Hau  1 , Han Shen  2 , Catherine Clark  3 , Peter H Graham  4 , Eng-Siew Koh  5 , Kerrie L McDonald  6
Affiliations
Review

The evolving roles and controversies of radiotherapy in the treatment of glioblastoma

Eric Hau et al. J Med Radiat Sci. 2016 Jun.

Abstract

Numerous randomised controlled trials have demonstrated the benefit of radiation therapy in patients with newly diagnosed glioblastoma and it has been the cornerstone of treatment for decades. The aims of this review are to (1) Briefly outline the historical studies which resulted in radiation being the current standard of care as used in the Stupp et al. trial (2) Discuss the evolving role of radiation therapy in the management of elderly patients (3) Review the current evidence and ongoing studies of radiation use in the recurrent/salvage setting and (4) Discuss the continuing controversies of volume delineation in the planning of radiation delivery.

Keywords: Brain tumour; glioblastoma; radiation; radiotherapy.

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References

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