Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2016 Nov;15(21):2854-2855.
doi: 10.1080/15384101.2016.1204868. Epub 2016 Jun 29.

A new function for p53 tetramerization domain in cell fate control

Jin Zhang  1 , Christopher Lucchesi  1 , Xinbin Chen  1
Affiliations
Comment

A new function for p53 tetramerization domain in cell fate control

Jin Zhang et al. Cell Cycle. 2016 Nov.
No abstract available

Keywords: Apoptosis; Cell cycle arrest; K351/357; acetylation; p53; tetramerization domain.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
A proposed model for the role of p53 tetramerization domain in cell fate control.
See this image and copyright information in PMC

Comment on

References

    1. Vousden KH, Prives C. Blinded by the Light: The Growing Complexity of p53. Cell 2009; 137(3):413-31; PMID:19410540; http://dx.doi.org/ 10.1016/j.cell.2009.04.037 - DOI - PubMed
    1. Chene P. The role of tetramerization in p53 function. Oncogene 2001; 20(21):2611-7; PMID:11420672; http://dx.doi.org/ 10.1038/sj.onc.1204373 - DOI - PubMed
    1. Beckerman R, et al.. Lysines in the tetramerization domain of p53 selectively modulate G1 arrest. Cell Cycle 2016; 15(11):1425-38; PMID:27210019; http://dx.doi.org/ 10.1080/15384101.2016.1170270 - DOI - PMC - PubMed
    1. Rowan S, et al.. Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant. EMBO J 1996; 15(4):827-38; PMID:8631304 - PMC - PubMed
    1. Sykes SM, et al.. Acetylation of the p53 DNA-binding domain regulates apoptosis induction. Mol Cell 2006; 24(6):841-51; PMID:17189187; http://dx.doi.org/ 10.1016/j.molcel.2006.11.026 - DOI - PMC - PubMed

Substances

LinkOut - more resources