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. 2016 Dec;63(8):579-583.
doi: 10.1111/zph.12276. Epub 2016 Jun 30.

No Evidence of Dengue Virus Infections in Several Species of Bats Captured in Central and Southern Mexico

S Cabrera-Romo  1 , C Max Ramirez  2 , B Recio-Tótoro  3 , J Tolentino-Chi  4 , H Lanz  3 , R M Del Ángel  1 , V Sánchez-Cordero  5 , Á Rodríguez-Moreno  5 , J E Ludert  1
Affiliations

No Evidence of Dengue Virus Infections in Several Species of Bats Captured in Central and Southern Mexico

S Cabrera-Romo et al. Zoonoses Public Health. 2016 Dec.

Abstract

Bats are reservoirs for viruses with zoonotic potential in the Americas, and scattered evidence exists suggesting that bats may act as reservoirs for dengue virus (DENV). To explore further the role of bats as part of DENV sylvatic cycles, 240 bats of 18 species were captured in 2 states of Mexico with contrasting ecological characteristics but concurrent DENV activity in humans. RT-PCR analysis of RNA extracted from liver or spleen tissue from de bats failed to show evidence for the presence of DENV nucleic acids in these organs. In addition, plasma assayed by plaque reduction neutralization test showed no evidence of neutralizing anti-DENV antibodies. These results suggest that American bats may not be reservoirs or amplification host for DENV infection.

Keywords: Dengue virus; Mexico; bats; dengue sylvatic cycle.

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