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. 2017 Jan;19(1):45-50.
doi: 10.1111/jch.12863. Epub 2016 Jun 30.

Distribution of Serum Uric Acid in Black Africans and Its Association With Cardiovascular Risk Factors

Stephanie R Moulin  1 , Marcelo P Baldo  1   2 , Juliana B Souza  1 , Weverton M Luchi  3 , Daniel P Capingana  4 , Pedro Magalhães  4 , José G Mill  1
Affiliations

Distribution of Serum Uric Acid in Black Africans and Its Association With Cardiovascular Risk Factors

Stephanie R Moulin et al. J Clin Hypertens (Greenwich). 2017 Jan.

Abstract

Hyperuricemia is associated with cardiovascular disease and its prevalence is unknown in black Africans. This study reports hyperuricemia distribution and its association with cardiovascular risk factors in a selected Angolan population. A cross-sectional study in 585 black Africans was performed. Hyperuricemia was defined as uric acid >7.0 mg/dL in men or >5.7 mg/dL in women. Overall prevalence was 25%. Hyperuricemia was associated with hypertension (odds ratio [OR], 2.20; confidence interval [CI], 95% 1.41-3.47), high waist circumference (OR, 1.67; CI, 95% 1.05-2.65), and metabolic syndrome (OR, 1.66; CI, 95% 1.07-2.57). Compared to those with uric acid levels in the first quartile, individuals in the fourth quartile showed higher body mass index, waist circumference, systolic blood pressure, and plasma levels of creatinine and triglycerides. Hypertension, high waist circumference, and metabolic syndrome were the major cardiovascular risk factors associated with hyperuricemia.

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Figures

Figure 1
Figure 1
Serum uric acid distribution by sex.
See this image and copyright information in PMC

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