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. 1978 Apr;31(4):313-5.
doi: 10.1136/jcp.31.4.313.

Bone marrow fibrosis in acute lymphoblastic leukaemia of childhood

I M Hann, D I Evans, H B Marsden, P M Jones, M K Palmer

Bone marrow fibrosis in acute lymphoblastic leukaemia of childhood

I M Hann et al. J Clin Pathol. 1978 Apr.

Abstract

A prospective study of bone marrow fibrosis was made in a group of 40 children with acute lymphoblastic leukaemia to see whether it affected the prognosis or course of the disease. Secondary myelofibrosis (SMF) was present at diagnosis in 57% of the cases. It was not statistically significantly related to the prognosis or course of the disease. Thus, although trephine biopsy occasionally provided useful information in different diagnosis and when aspiration was difficult, it provided little information of use for management.

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References

    1. J Clin Pathol. 1962 Sep;15(5):394-400 - PubMed
    1. Blood. 1964 Apr;23:526-44 - PubMed
    1. Br J Haematol. 1963 Apr;9:172-84 - PubMed
    1. Blood. 1951 Apr;6(4):372-5 - PubMed
    1. Br J Cancer. 1977 Jan;35(1):1-39 - PubMed

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