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. 2016 Jul;55(1):150-1.
doi: 10.1165/rcmb.2015-0403LE.

Significant Interference in Mass Cytometry from Medicinal Iodine in Human Lung

Brian C Keller  1   2 , Rachel M Presti  1 , Derek E Byers  1 , Jeffrey J Atkinson  1
Affiliations

Significant Interference in Mass Cytometry from Medicinal Iodine in Human Lung

Brian C Keller et al. Am J Respir Cell Mol Biol. 2016 Jul.
No abstract available

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Figures

Figure 1.
Figure 1.
Normal mass cytometry result with mild contamination. Typical mass cytometry results demonstrate signal (dots) in one of 30+ activated detectors as the ion cloud of individual cells are pushed through the detector. On the y axis is the push number, and on the x axis is the individual mass channels. This sample is a human mononuclear preparation labeled with metal-conjugated antibodies for CD45, CD14, CD16, HLA-DR, and two DNA intercalators. A CD45+CD14+CD16+HLA-DR+ monocyte and CD45+CD3+ lymphocyte are pictured. The two detector lanes (I, Ba) next to the CD45 lane demonstrate mild environmental contamination, with 127I and 138Ba, respectively, resulting in continuous signal that is not cell associated.
See this image and copyright information in PMC

References

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