Synthesis, characterization and evaluation of antibacterial activity of (E)-N'-(substituted benzylidene)-2-(2-fluorobenzyl)-5-ethyl-2H-1,2,3-triazole-4-carbohydrazides

Abstract

Triazoles and their derivatives are important precursors in the pharmacological field due to their broad diversity of medicinal and biological deed. In this article, the exploration is to put an effort to produce some novel biologically active triazole 4-carbohydrazide derivatives. The structures of the newly synthesized compounds were characterized and confirmed by spectral data and were screened for anti-bacterial activity. Compounds 5(d-i), 5l and 5m were observed to possess potent anti-microbial activity.

Keywords: Activité antibactérienne; Antibacterial activity; Synthesis of triazoles; Synthèse de triazoles substitués.