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Case Reports
. 2016 Jul;29(3):323-4.
doi: 10.1080/08998280.2016.11929454.

An atypical presentation of blue rubber bleb nevus syndrome

Affiliations
Case Reports

An atypical presentation of blue rubber bleb nevus syndrome

Jessica Gonzalez-Hernandez et al. Proc (Bayl Univ Med Cent). 2016 Jul.

Abstract

A 69-year-old white man presented with several episodes of hematochezia. Colonoscopy demonstrated multiple colonic blebs localized mainly in the distal transverse colon. Esophagogastroduodenoscopy, capsule endoscopy, and computed tomography of the abdomen did not reveal any abnormalities. The patient required several blood transfusions and eventually required a subtotal colectomy with ileosigmoid anastomosis for definitive bleeding control. Pathology was remarkable for multifocal vascular ectasia, consistent with the diagnosis of blue rubber bleb nevus syndrome.

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Figures

Figure 1.
Figure 1.
Colonoscopy showing multiple colonic blebs in the transverse colon.
Figure 2.
Figure 2.
Surgical specimen of the colon with multiple blue to black rubbery blood-filled sacs.
Figure 3.
Figure 3.
Multifocal vascular ectasia with hemorrhage involving mucosa and submucosa.

References

    1. Gascoyen GG. Case of nevus involving the parotid gland and causing death from suffocation: nevi of the viscera. Trans Pathol Soc Lond. 1860;11:267–270.
    1. Kaur T. Singh S. Blue rubber bleb nevus syndrome: a case report. Indian J Dermatol. 2014;59(1):98–99. - PMC - PubMed
    1. Oksüzoğlu BC. Oksüzoğlu G. Cakir U. Bayir T. Esen M. Blue rubber bleb nevus syndrome. Am J Gastroenterol. 1996;91(4):780–782. - PubMed
    1. Moodley M. Ramdial P. Blue rubber bleb nevus syndrome: case report and review of the literature. Pediatrics. 1993;92(1):160–162. - PubMed
    1. Zahedi MJ. Darvish Moghadam S. Seyed Mirzaei SM. Dehghani M. Shafiei Pour S. Rasti A. Blue rubber bleb nevus syndrome as a rare cause of iron deficiency anemia: a case report and review of literature. Middle East J Dig Dis. 2013;5(4):235–239. - PMC - PubMed

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