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Review
. 2016 Jun 18;9(6):904-13.
doi: 10.18240/ijo.2016.06.20. eCollection 2016.

Characteristics of corneal dystrophies: a review from clinical, histological and genetic perspectives

Ze-Nan Lin  1 , Jie Chen  1 , Hong-Ping Cui  1
Affiliations
Review

Characteristics of corneal dystrophies: a review from clinical, histological and genetic perspectives

Ze-Nan Lin et al. Int J Ophthalmol. .

Abstract

Corneal dystrophy is a common type of hereditary corneal diseases. It includes many types, which have varied pathology, histology and clinical manifestations. Recently, the examination techniques of ophthalmology and gene sequencing advance greatly, which do benefit to our understanding of these diseases. However, many aspects remain still unknown. And due to the poor knowledge of these diseases, the results of the treatments are not satisfoctory. The purpose of this review was to summarize the clinical, histological and genetic characteristics of different types of corneal dystrophies.

Keywords: clinic; corneal dystrophy; gene mutation; histology.

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Figures

Figure 1
Figure 1. Gelatinous drop-like dystrophy, courtesy of Dr. GK Klintworth.
Figure 2
Figure 2. Granular corneal dystrophy (Groenouw type I).
Figure 3
Figure 3. Light microscopy of GCD I. Masson Trichrome stain, courtesy of Dr. GK Klintworth.
Figure 4
Figure 4. Fuchs endothelial corneal dystrophy, courtesy of Dr. GK Klintworth.
Figure 5
Figure 5. Light microscopy of FECD, PAS stain. Courtesy of Dr. GK Klintworth.
See this image and copyright information in PMC

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