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. 2016 Nov-Dec;10(6):728-733.
doi: 10.1016/j.orcp.2016.06.006. Epub 2016 Jul 2.

Intestinal methane production is associated with decreased weight loss following bariatric surgery

Ruchi Mathur  1 , Manpreet S Mundi  2 , Kathleen S Chua  3 , Paul A Lorentz  2 , Gillian M Barlow  3 , Eugenia Lin  3 , Miguel Burch  4 , Adrienne Youdim  4 , Mark Pimentel  3
Affiliations

Intestinal methane production is associated with decreased weight loss following bariatric surgery

Ruchi Mathur et al. Obes Res Clin Pract. 2016 Nov-Dec.

Abstract

To determine whether methane and hydrogen on breath test affects weight loss after bariatric surgery, 156 subjects (pre-surgery BMI ≥33) were recruited ≥4 months after surgery. Pre- and post-surgery weights and BMIs were recorded. Post-surgery methane and hydrogen levels were determined. % total weight loss and % change in BMI were prorated to six months after surgery. M+/H+ subjects (N=13) exhibited lower prorated % change in BMI vs. all other subjects (N=144) (p=0.13), and significantly lower prorated % total weight loss (p=0.036). These findings may suggest that subjects with positive breath methane and hydrogen lose less weight following bariatric surgery.

Keywords: Bariatric surgery; Breath test; Methane; Methanogen.

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