Congenital third nerve palsy with synergistic depression on attempted adduction and trigemino-oculomotor synkinesis: Underpinnings of a spectral dysinnervation disorder
- PMID: 27380983
- PMCID: PMC4966381
- DOI: 10.4103/0301-4738.185628
Congenital third nerve palsy with synergistic depression on attempted adduction and trigemino-oculomotor synkinesis: Underpinnings of a spectral dysinnervation disorder
Abstract
The authors describe a case of congenital partial pupil-sparing third cranial nerve palsy with absent adduction, synergistic depression of globe and widening of palpebral fissure on attempted adduction and synergistic elevation and adduction on mouth opening and sideways thrusting of jaw. The case illustrates trigemino-oculomotor synkinesis associated with congenital third nerve palsy. The possible mechanism of miswiring involving the medial longitudinal fasciculus and trigeminal nuclei is discussed. At least some cases of congenital third cranial nerve palsy may fall in the realm of congenital cranial dysinnervation disorders (CCDDs) sharing a much wider spectrum of presentation.
Figures
References
-
- Hamed LM, Dennehy PJ, Lingua RW. Synergistic divergence and jaw-winking phenomenon. J Pediatr Ophthalmol Strabismus. 1990;27:88–90. - PubMed
-
- Brodsky MC. Hereditary external ophthalmoplegia synergistic divergence, jaw winking, and oculocutaneous hypopigmentation: A congenital fibrosis syndrome caused by deficient innervation to extraocular muscles. Ophthalmology. 1998;105:717–25. - PubMed
-
- Khan AO. A novel form of aberrant innervation in congenital cranial dysinnervation disorder. J AAPOS. 2009;13:105–6. - PubMed
-
- Kassem IS, Kodsi SR. Marcus Gunn jaw winking with trigemino-oculomotor synkinesis of the inferior division of the oculomotor nerve. J AAPOS. 2009;13:315–6. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical