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. 2016 Oct;26(10):2516-22.
doi: 10.1007/s11695-016-2280-3.

Monitoring of Liver Function Tests after Roux-en-Y Gastric Bypass: An Examination of Evidence Base

Kamal K Mahawar  1   2 , Chetan Parmar  3 , Yitka Graham  3   4 , Nimantha De Alwis  3 , William R J Carr  3 , Neil Jennings  3 , Peter K Small  3
Affiliations

Monitoring of Liver Function Tests after Roux-en-Y Gastric Bypass: An Examination of Evidence Base

Kamal K Mahawar et al. Obes Surg. 2016 Oct.

Abstract

There is no consensus on the monitoring of liver function tests after Roux-en-Y gastric bypass (RYGB). Since the main objective of such monitoring would be to diagnose early those who will eventually develop liver failure after RYGB, we performed a systematic review on this topic. An extensive search of literature revealed only 10 such cases in 6 published articles. It would hence appear that liver failure is a rare problem after RYGB. Routine lifelong monitoring of liver function tests is therefore unnecessary for otherwise asymptomatic individuals. Such monitoring should hence be reserved for high-risk groups, such as patients with liver cirrhosis, those undergoing extended limb/distal RYGB, patients with new illnesses, those abusing alcohol, those on hepatotoxic drugs and those presenting with a surgical complication.

Keywords: Follow-up; Gastric bypass; Liver decompensation; Liver failure; Liver function tests; Roux-en-Y gastric bypass.

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