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Review
. 2016 Jun 23:12:1525-38.
doi: 10.2147/NDT.S84585. eCollection 2016.

Aggression in autism spectrum disorder: presentation and treatment options

Sarah E Fitzpatrick  1 , Laura Srivorakiat  1 , Logan K Wink  1 , Ernest V Pedapati  1 , Craig A Erickson  1
Affiliations
Review

Aggression in autism spectrum disorder: presentation and treatment options

Sarah E Fitzpatrick et al. Neuropsychiatr Dis Treat. .

Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by persistent difficulties in social communication and social interaction, coupled with restricted, repetitive patterns of behavior or interest. Research indicates that aggression rates may be higher in individuals with ASD compared to those with other developmental disabilities. Aggression is associated with negative outcomes for children with ASD and their caregivers, including decreased quality of life, increased stress levels, and reduced availability of educational and social support. Therapeutic strategies including functional behavioral assessment, reinforcement strategies, and functional communication training may have a significant impact in reducing the frequency and intensity of aggressive behavior in individuals with ASD. Pharmacologic treatments, particularly the use of second-generation antipsychotics, may also be of some benefit in reducing aggression in individuals with ASD. With the ever-increasing rate of ASD diagnosis, development of effective therapeutic and pharmacologic methods for preventing and treating aggression are essential to improving outcomes in this disorder.

Keywords: aggression; antipsychotics; applied behavior analysis; autism; autism spectrum disorder; treatment.

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References

    1. American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders: DSM-5. Spring Hill, TN: ManMag; 2003.
    1. Hastings RP, Kovshoff H, Ward NJ, degli Espinosa F, Brown T, Remington B. Systems analysis of stress and positive perceptions in mothers and fathers of pre-school children with autism. J Autism Dev Disord. 2005;35(5):635–644. - PubMed
    1. Lecavalier L, Leone S, Wiltz J. The impact of behaviour problems on caregiver stress in young people with autism spectrum disorders. J Intellect Disabil Res. 2006;50(3):172–183. - PubMed
    1. Aman M, Singh N. Aberrant Behavior Checklist: Manual. East Aurora, NY: Slosson Educational Publications; 1986.
    1. Kaartinen M, Puura K, Helminen M, Salmelin R, Pelkonen E, Juujärvi P. Reactive aggression among children with and without autism spectrum disorder. J Autism Dev Disord. 2014;44(10):2383–2391. - PubMed