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Comment
. 2016 Sep;12(9):503-4.
doi: 10.1038/nrrheum.2016.113. Epub 2016 Jul 7.

Osteoarthritis: Bone as an imaging biomarker and treatment target in OA

Tuhina Neogi  1 , David T Felson  1
Affiliations
Comment

Osteoarthritis: Bone as an imaging biomarker and treatment target in OA

Tuhina Neogi et al. Nat Rev Rheumatol. 2016 Sep.

Abstract

Radiographic joint-space width is the standard structural outcome for trials in knee osteoarthritis (OA), but MRI provides comprehensive 3D insights into the multi-tissue pathology of OA and could provide a superior means of monitoring disease progression and response to treatment. A new study highlights bone as an imaging biomarker.

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Conflict of interest statement

statement The authors declare no competing interests.

Figures

Figure 1
Figure 1. 3D femur bone shape changes in osteoarthritis
As knee bone shape changes to more of an osteoarthritis (OA) shape, the femoral changes include widening and flattening of the condyles, with a ridge of osteophytic growth around the cartilage plate. Image courtesy of Michael A. Bowes, Imorphics Ltd, Manchester, UK.
See this image and copyright information in PMC

Comment on

References

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