Is afatinib a treatment option for brain metastases in patients with EGFR mutation-positive non-small cell lung cancer?
- PMID: 27385269
- PMCID: PMC4916360
- DOI: 10.21037/atm.2016.05.48
Is afatinib a treatment option for brain metastases in patients with EGFR mutation-positive non-small cell lung cancer?
Conflict of interest statement
Comment on
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First-Line Afatinib versus Chemotherapy in Patients with Non-Small Cell Lung Cancer and Common Epidermal Growth Factor Receptor Gene Mutations and Brain Metastases.J Thorac Oncol. 2016 Mar;11(3):380-90. doi: 10.1016/j.jtho.2015.11.014. Epub 2016 Jan 25. J Thorac Oncol. 2016. PMID: 26823294 Clinical Trial.
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- Mitsudomi T, Morita S, Yatabe Y, et al. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial. Lancet Oncol 2010;11:121-8. 10.1016/S1470-2045(09)70364-X - DOI - PubMed
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