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Case Reports
. 1989 Apr;52(4):536-8.
doi: 10.1136/jnnp.52.4.536.

Peripheral neuropathy associated with mycosis fungoides

M Comola  1 , R Nemni, G Comi, M Corbo, G Taccagni, C Besana, N Canal
Affiliations
Case Reports

Peripheral neuropathy associated with mycosis fungoides

M Comola et al. J Neurol Neurosurg Psychiatry. 1989 Apr.

Abstract

A 56 year old man with acute sensory-motor polyneuropathy associated with mycosis fungoides is described. EMG studies showed diffuse signs of muscle denervation. A skin biopsy specimen showed a lymphocyte infiltration in the dermis, composed of mycosis cells characterised by deep invaginations of the nuclear membrane, and small Pautrier's microabscesses in the epidermis. Sural nerve biopsy revealed endoneurial fibrosis, a decreased number of myelinated fibres and acute axonal degeneration.

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