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Clinical Trial
. 2016 Oct;101(10):e415-e418.
doi: 10.3324/haematol.2016.146092. Epub 2016 Jul 6.

Baseline bone involvement in multiple myeloma - a prospective comparison of conventional X-ray, low-dose computed tomography, and 18flourodeoxyglucose positron emission tomography in previously untreated patients

Maja Hinge  1 , Kristian T Andersen  2 , Thomas Lund  3 , Henrik B Jørgensen  4 , Paw C Holdgaard  4 , Tina E Ormstrup  5 , Lone L Østergaard  5 , Torben Plesner  2
Affiliations
Clinical Trial

Baseline bone involvement in multiple myeloma - a prospective comparison of conventional X-ray, low-dose computed tomography, and 18flourodeoxyglucose positron emission tomography in previously untreated patients

Maja Hinge et al. Haematologica. 2016 Oct.
No abstract available

Keywords: CT; Myeloma; PET; X-ray; bone marker.

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Figures

Figure 1.
Figure 1.
Low-dose CT versus conventional X-ray. Low-dose CT (A) and conventional X-ray (B) of a 67-year-old man with newly diagnosed multiple myeloma. X-ray performed 7 days after low-dose CT-scanning. The CT-scan shows a significant osteolytic lesion, not visualised at X-ray, of the pelvic area.
Figure 2.
Figure 2.
Imminent medullary compression revealed by low-dose CT. The low-dose CT-scan reveals tumor growth in the vertebral canal (A). This lesion was PET-positive (B). MR-scan confirmed the intra-spinal growth (C). The patient was asymptomatic.
Figure 3.
Figure 3.
Results of X-ray, low-dose CT and PET. The individual results of the different imaging methods performed at baseline for the 35 previously untreated multiple myeloma patients. Below the columns are the numbers of positive, negative and missing results of each imaging modality shown. Low-dose CT identifies most patients with osteolysis. Black squares illustrate osteolysis at low-dose CT (CT), conventional X-rays (X-ray), and focal activity at 18FDG-PET (PET), while white squares illustrate imaging without osteolysis of focal activity. Grey squares represent missing data.
See this image and copyright information in PMC

References

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