Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Apr 3:30:348.
eCollection 2016.

Health technology assessment of non-invasive interventions for weight loss and body shape in Iran

Marzieh Nojomi  1 , Maziar Moradi-Lakeh  2 , Ashraf Velayati  3 , Ahmad Naghibzadeh-Tahami  4 , Haleh Dadgostar  5 , Gholamhossein Ghorabi  6 , Mohammad Moradi-Joo  7 , Mohsen Yaghoubi  8
Affiliations

Health technology assessment of non-invasive interventions for weight loss and body shape in Iran

Marzieh Nojomi et al. Med J Islam Repub Iran. .

Abstract

Background: The burden of obesity and diet-related chronic diseases is increasing in Iran, and prevention and treatment strategies are needed to address this problem. The aim of this study was to determine the outcome, cost, safety and cost-consequence of non-invasive weight loss interventions in Iran.

Methods: We performed a systematic review to compare non-invasive interventions (cryolipolysis and radiofrequency/ ultrasonic cavitation) with semi-invasive (lipolysis) and invasive (liposuction). A sensitive electronic searching was done to find available interventional studies. Reduction of abdomen circumference (cm), reduction in fat layer thickness (%) and weight reduction (kg) were outcomes of efficacy. Meta-analysis with random models was used for pooling efficacy estimates among studies with the same follow-up duration. Average cost per intervention was estimated based on the capital, maintenance, staff, consumable and purchase costs.

Results: Of 3,111 studies identified in our reviews, 13 studies assessed lipolysis, 10 cryolipolysis and 8 considered radiofrequency. Nine studies with the same follow-up duration in three different outcome group were included in meta-analysis. Radiofrequency showed an overall pooled estimate of 2.7 cm (95% CI; 2.3-3.1) of mean reduction in circumference of abdomen after intervention. Pooled estimate of reduction in fat layer thickness was 78% (95% CI; 73%-83%) after Lipolysis and a pooled estimate of weight loss was 3.01 kg (95% CI; 2.3-3.6) after lipousuction. The cost analysis revealed no significant differences between the costs of these interventions.

Conclusion: The present study showed that non-invasive interventions appear to have better clinical efficacy, specifically in the body shape measurement, and less cost compared to invasive intervention (liposuction).

Keywords: Consequence; Cost; Cryolipolysis; Lipolysis; Liposuction; Meta-analysis; Radiofrequency; Systematic review.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Orlet fisher J. How important is it? Synthesis of expert's text. April 2012.
    1. Canadian clinical practice guidelines on the management and prevention of obesity in adults and children 2007 April 10;176(8). - PMC - PubMed
    1. Frood S, Johnston LM, Matteson CL, Finegood DT. Obesity, Complexity, and the Role of the Health System. Curr Obes Rep. 2013;2(4):320–326. - PMC - PubMed
    1. Guidance on the prevention, identification, assessment and management of overweight and obesity in adults and children .National Institute for Health and clinical excellence. Dec 2006. - PubMed
    1. Exilis, the Latest Device for Non-Invasive Skin Tightening and Non-Surgical Fat Reduction, Aesthetic Solutions-Dermatology, Laser and Researc, PR Log - Global Press Release Distribution, 2011;.

LinkOut - more resources