Heat Shock Factor 1: From Fire Chief to Crowd-Control Specialist
- PMID: 27392142
- DOI: 10.1016/j.molcel.2016.06.026
Heat Shock Factor 1: From Fire Chief to Crowd-Control Specialist
Abstract
HSF1 is the supposed master regulator of the heat shock response. In this issue of Molecular Cell, Solís et al. reveal that it has a much narrower job description: organizing a small team of molecular chaperones that keep the proteome moving.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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Mammalian Heat Shock Response and Mechanisms Underlying Its Genome-wide Transcriptional Regulation.Mol Cell. 2016 Apr 7;62(1):63-78. doi: 10.1016/j.molcel.2016.02.025. Epub 2016 Mar 24. Mol Cell. 2016. PMID: 27052732 Free PMC article.
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Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis.Mol Cell. 2016 Jul 7;63(1):60-71. doi: 10.1016/j.molcel.2016.05.014. Epub 2016 Jun 16. Mol Cell. 2016. PMID: 27320198 Free PMC article.
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