doi: 10.1038/340035a0.
Expression of a large family of POU-domain regulatory genes in mammalian brain development
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- PMID: 2739723
- DOI: 10.1038/340035a0
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Expression of a large family of POU-domain regulatory genes in mammalian brain development
Nature.
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Erratum in
- Nature 1989 Aug 24;340(6235):662
Abstract
A novel region referred to as the POU-domain is present in two tissue-specific transcription factors, Pit-1 and Oct-2, that activate expression of genes specifying pituitary and lymphocyte phenotypes. We report the identification of multiple new members of a large family of POU-domain genes expressed in adult brain, and document that all the known mammalian POU-domain genes, including Pit-1 and Oct-2, are expressed widely in the developing nervous system.
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