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. 1989 Jul 6;340(6228):35-41.
doi: 10.1038/340035a0.

Expression of a large family of POU-domain regulatory genes in mammalian brain development

X He  1 , M N Treacy, D M Simmons, H A Ingraham, L W Swanson, M G Rosenfeld
Affiliations

Expression of a large family of POU-domain regulatory genes in mammalian brain development

X He et al. Nature. .

Erratum in

  • Nature 1989 Aug 24;340(6235):662

Abstract

A novel region referred to as the POU-domain is present in two tissue-specific transcription factors, Pit-1 and Oct-2, that activate expression of genes specifying pituitary and lymphocyte phenotypes. We report the identification of multiple new members of a large family of POU-domain genes expressed in adult brain, and document that all the known mammalian POU-domain genes, including Pit-1 and Oct-2, are expressed widely in the developing nervous system.

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