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. 1989;36(3):305-15.

Effects of benfluron metabolites on glycolysis and level of thiol groups in P388 and Ehrlich ascites cells

M Miko  1 , J Krepelka, M Mĕlka, D Vajdová
Affiliations
  • PMID: 2739809

Effects of benfluron metabolites on glycolysis and level of thiol groups in P388 and Ehrlich ascites cells

M Miko et al. Neoplasma. 1989.

Abstract

The effects of two benfluron metabolites, namely 7-dihydrobenfluron (DBF) and N-oxide of benfluron (NOBF), on the aerobic glycolysis of Ehrlich ascites carcinoma (EAC) and P388 cells were studied. Also their effect on the level of total (T-SH) and nonprotein (NP-SH) thiol groups was investigated. A significant inhibition of aerobic glycolysis in the presence of NOBF was found only in P388 cells. Both metabolites decreased more significantly the level of NP-SH than that of T-SH.

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