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Review
. 2016 Jul 8;14(7):129.
doi: 10.3390/md14070129.

Spotlight on Antimicrobial Metabolites from the Marine Bacteria Pseudoalteromonas: Chemodiversity and Ecological Significance

Clément Offret  1 , Florie Desriac  2 , Patrick Le Chevalier  3 , Jérôme Mounier  4 , Camille Jégou  5 , Yannick Fleury  6
Affiliations
Review

Spotlight on Antimicrobial Metabolites from the Marine Bacteria Pseudoalteromonas: Chemodiversity and Ecological Significance

Clément Offret et al. Mar Drugs. .

Abstract

This review is dedicated to the antimicrobial metabolite-producing Pseudoalteromonas strains. The genus Pseudoalteromonas hosts 41 species, among which 16 are antimicrobial metabolite producers. To date, a total of 69 antimicrobial compounds belonging to 18 different families have been documented. They are classified into alkaloids, polyketides, and peptides. Finally as Pseudoalteromonas strains are frequently associated with macroorganisms, we can discuss the ecological significance of antimicrobial Pseudoalteromonas as part of the resident microbiota.

Keywords: Pseudoalteromonas; alkaloid; antimicrobial metabolites; genome mining; marine host-associated microbiota; non ribosomal peptide; polyketide; probiotic.

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Figures

Figure 1
Figure 1
Neighbor-joining tree indicating the phylogenetic relationships inferred from partial 16S rDNA gene sequences (1196 nt) of Pseudoalteromonas strains producing either alkaloids (green), polyketides (red), or peptides (blue). Empty circles represent strains producing unidentified antimicrobial compounds. Bootstrap values (expressed as percentage of 1000 replications) > 50% are shown at branching points. The proteobacteria Escherichia coli 2012K11 (position 167-1356) was used as outgroup. Bar, 0.01 substitutions per nucleotide.
See this image and copyright information in PMC

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