Two Cases of Paradoxical Hidradenitis Suppurativa while on Adalimumab
- PMID: 27403108
- PMCID: PMC4929363
- DOI: 10.1159/000444442
Two Cases of Paradoxical Hidradenitis Suppurativa while on Adalimumab
Abstract
Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease characterized by recurring abscesses, nodules, and fistulas predominantly in the groin and axillae. The association between HS and Crohn's disease (CD) has been well documented. Tumor necrosis factor (TNF) inhibitors have shown to be effective in treating both HS and CD. We report 2 patients who developed HS while on TNF inhibitor treatment for CD.
Keywords: Adalimumab; Crohn's disease; Hidradenitis Suppurativa.
Figures
Similar articles
-
Adalimumab treatment for hidradenitis suppurativa associated with Crohn's disease.Acta Dermatovenerol Croat. 2014;22(4):291-3. Acta Dermatovenerol Croat. 2014. PMID: 25580790
-
Hidradenitis Suppurativa as a Paradoxical Side Effect to the Use of Adalimumab in Patients with Crohn's Disease?Clin Exp Gastroenterol. 2020 Aug 19;13:293-298. doi: 10.2147/CEG.S263685. eCollection 2020. Clin Exp Gastroenterol. 2020. PMID: 32943900 Free PMC article.
-
Increased risk of permanent stoma in Crohn's disease associated with hidradenitis suppurativa: a case-control study.Aliment Pharmacol Ther. 2020 Jul;52(2):303-310. doi: 10.1111/apt.15863. Epub 2020 Jun 11. Aliment Pharmacol Ther. 2020. PMID: 32525586
-
Paradoxical hidradenitis suppurativa in Crohn's disease patients receiving infliximab: a case report and review of literature.Eur J Gastroenterol Hepatol. 2021 Dec 1;33(1S Suppl 1):e1046-e1050. doi: 10.1097/MEG.0000000000002170. Eur J Gastroenterol Hepatol. 2021. PMID: 33905217 Review.
-
Association of hidradenitis suppurativa with Crohn's disease.World J Clin Cases. 2021 May 26;9(15):3506-3516. doi: 10.12998/wjcc.v9.i15.3506. World J Clin Cases. 2021. PMID: 34046451 Free PMC article. Review.
Cited by
-
Paradoxical Hidradenitis Suppurativa during Biologic Therapy, an Emerging Challenge: A Systematic Review.Biomedicines. 2022 Feb 16;10(2):455. doi: 10.3390/biomedicines10020455. Biomedicines. 2022. PMID: 35203664 Free PMC article. Review.
-
Drug-Induced Hidradenitis Suppurativa: A Case Report.Cureus. 2023 Nov 29;15(11):e49637. doi: 10.7759/cureus.49637. eCollection 2023 Nov. Cureus. 2023. PMID: 38161925 Free PMC article.
References
-
- Danby FW, Margesson LJ. Hidradenitis suppurativa. Dermatol Clin. 2010;28:779–793. - PubMed
-
- Kamal N, Cohen BL, Buche S, Delaporte E, Colombel JF. Features of patients with Crohn's disease and hidradenitis suppurativa. Clin Gastroenterol Hepatol. 2016;14:71–79. - PubMed
-
- Kimball AB, Kerdel F, Adams D, et al. Adalimumab for the treatment of moderate to severe Hidradenitis suppurativa: a parallel randomized trial. Ann Intern Med. 2012;157:846–855. - PubMed
-
- Hanauer SB, Sandborn WJ, Rutgeerts P, et al. Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial. Gastroenterology. 2006;130:323–333. quiz 591. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources