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. 2016:2016:3545180.
doi: 10.1155/2016/3545180. Epub 2016 Jun 14.

Evaluation of Choroidal Thickness in Patients with Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma

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Evaluation of Choroidal Thickness in Patients with Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma

Ayhan Dursun et al. J Ophthalmol. 2016.

Abstract

Purpose. To compare the macular and peripapillary choroidal thickness in eyes with pseudoexfoliation (PEX) syndrome and PEX glaucoma with the normal eyes of healthy controls. Materials and Methods. In this prospective study, 30 eyes of 30 patients with PEX syndrome, 28 eyes of 28 patients with PEX glaucoma, and 30 eyes of 30 age-matched healthy subjects were enrolled. Choroidal thicknesses in the macular and peripapillary areas were measured by using spectral domain optical coherence tomography. Results. Gender, age, and axial length did not significantly differ between the groups (all, p > 0.05). The mean values of choroidal thickness in the macular and peripapillary areas (except the superior quadrant) in the patients with PEX syndrome and PEX glaucoma were lower compared with controls (all p < 0.05). The mean values of the macular and peripapillary choroidal thickness in the PEX glaucoma group were lower compared with PEX syndrome group; however this difference was not significant. Conclusions. The findings of this study revealed that macular and peripapillary choroidal thicknesses were decreased in PEX syndrome and PEX glaucoma cases. The role of choroid in the development of glaucomatous damage in patients with PEX syndrome remains unclear.

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Figures

Figure 1
Figure 1
Optical coherence tomography scan, showing the macular choroidal thicknesses at five different locations (subfoveal, 1.5 mm nasal to the fovea, 3 mm nasal to the fovea, 1.5 mm temporal to the fovea, and 3 mm temporal to the fovea).
Figure 2
Figure 2
Measurement of peripapillary choroidal thickness patient with PEX glaucoma. Yellow arrow indicates the choroidal thickness in the superior quadrant.

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References

    1. Mitchell P., Wang J. J., Hourihan F. The relationship between glaucoma and pseudoexfoliation: the Blue Mountains Eye Study. Archives of Ophthalmology. 1999;117(10):1319–1324. doi: 10.1001/archopht.117.10.1319. - DOI - PubMed
    1. Ritch R., Schlötzer-Schrehardt U. Exfoliation syndrome. Survey of Ophthalmology. 2001;45(4):265–315. doi: 10.1016/S0039-6257(00)00196-X. - DOI - PubMed
    1. Davanger M., Ringvold A., Blika S. Pseudo-exfoliation, IOP and glaucoma. Acta Ophthalmologica. 1991;69(5):569–573. - PubMed
    1. Streeten B. W., Li Z.-Y., Wallace R. N., Eagle R. C., Jr., Keshgegian A. A. Pseudoexfoliative fibrillopathy in visceral organs of a patient with pseudoexfoliation syndrome. Archives of Ophthalmology. 1992;110(12):1757–1762. doi: 10.1001/archopht.1992.01080240097039. - DOI - PubMed
    1. Schlotzer-Schrehardt U., Küchle M., Naumann G. O. H. Electron-microscopic identification of pseudoexfoliation material in extrabulbar tissue. Archives of Ophthalmology. 1991;109(4):565–570. doi: 10.1001/archopht.1991.01080040133044. - DOI - PubMed

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