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. 2016:2016:7536304.
doi: 10.1155/2016/7536304. Epub 2016 Jun 15.

A Review and Report of Peripheral Giant Cell Granuloma in a 4-Year-Old Child

Afsaneh Nekouei  1 , Alireza Eshghi  1 , Parisa Jafarnejadi  1 , Zahra Enshaei  1
Affiliations

A Review and Report of Peripheral Giant Cell Granuloma in a 4-Year-Old Child

Afsaneh Nekouei et al. Case Rep Dent. 2016.

Abstract

Peripheral giant cell granuloma is a common benign and reactive gingival epulis in oral cavity. It is often difficult to make a clinical diagnosis; thereby definitive diagnosis depends on histopathologic features. We report a case of a 4-year-old Caucasian boy presenting with a five-month history a 20 × 15 × 12 mm pedunculated, lobular soft tissue mass of the left anterior maxilla gingiva which was misdiagnosed and maltreated before his referral. An excisional biopsy of the lesion followed by histopathologic examination of the biopsy specimen revealed distinctive features of peripheral giant cell granuloma. Early detection and excision of this hyperplastic nodule especially in children are important to minimize potential dentoalveolar complications.

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Figures

Figure 1
Figure 1
Intraoral preoperative view of lesion: a painless red enlargement of the maxillary attached gingiva extends to the alveolar mucosa between teeth #52 and 53.
Figure 2
Figure 2
Intraoral periapical radiograph, showing superficial erosion of the alveolar bone.
Figure 3
Figure 3
Intraoral immediate postoperative view showing complete surgical removal.
Figure 4
Figure 4
Histopathologic section: hyperplastic granulation tissue, the presence of acute and chronic inflammatory cells, capillaries, and proliferation of multinucleated giant cells within haemorrhagic background showing histological appearance of the PGCG lesion (H&E stain 10x and 40x).
See this image and copyright information in PMC

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