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. 1989 Mar;21(2):151-4.
doi: 10.1016/0147-619x(89)90060-7.

Transferable 5-nitroimidazole resistance in the Bacteroides fragilis group

J Breuil  1 , A Dublanchet, N Truffaut, M Sebald
Affiliations

Transferable 5-nitroimidazole resistance in the Bacteroides fragilis group

J Breuil et al. Plasmid. 1989 Mar.

Abstract

We report the characterization of a strain of Bacteroides vulgatus, BV17, that exhibits a moderate resistance to 5-nitroimidazoles and carries plasmids of 4.5, 5, 7.7, and 56 kb. A genetic determinant involved in this resistance is carried by the 7.7 +/- 0.2-kb plasmid (pIP417). This plasmid can be introduced and replicated in a sensitive strain of B. fragilis 638R by transformation or by conjugation. In the latter case, the transfer may involve mobilization by the 56-kb conjugative plasmid (pIP418) regularly found in transconjugants but not in transformants.

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